产品货号：
Z17229
中文名称：
GRID2抗体
英文名称：
Anti-GRID2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRID2 Antibody |
| 指标别名 | glutamate ionotropic receptor delta type subunit 2;GluD2;SCAR18;GRID2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | GRID2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human GRID2 (KKDDEVFRTAVGDLNQN). |
| 实际分子量 | 113KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutamate receptor,ionotropic,delta 2,also known as GluD2,GluRδ2,or δ2,is a protein that in humans is encoded by the GRID2 gene.The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain.The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells.A point mutation in the mouse ortholog,associated with the phenotype named 'lurcher',in the heterozygous state leads to ataxia resulting from selective,cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development.Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis.This protein also plays a role in synapse organization between parallel fibers and Purkinje cells.Alternate splicing results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause cerebellar ataxia in humans. |
| Uniprot ID | O43424 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | glutamate ionotropic receptor delta type subunit 2 |
| 蛋白名全称 | Glutamate receptor ionotropic,delta-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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